Reviewing Recent Progress in Investigations of Calorie Restriction and Fasting A great deal of present day research is in one way or another focused on forms of lowered calorie intake. There are those who seek to fully map the mechanisms by which calorie restriction and intermittent fasting improve health and extend life significantly in short […]
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Can Systems Analysis Approaches Provide Insight into the Mechanisms of Aging?
Can Systems Analysis Approaches Provide Insight into the Mechanisms of Aging? Given enough data from enough old people, to what degree could modern approaches to information processing be used to derive useful information about the underlying mechanisms of aging? Such as which of the varied collection of causes and consequences involved in the biochemistry of […]
Resistance Training Correlates with Reduced Risk of Cardiovascular Disease
Resistance Training Correlates with Reduced Risk of Cardiovascular Disease As one of many continuations of recent efforts to quantify the benefits of various forms of exercise, researchers here find an association between resistance training and reduced risk of cardiovascular disease. The association is fairly binary; people undertaking any meaningful degree of resistance training show the […]
USP13 Inhibition Clears Lewy Bodies in a Mouse Model of Parkinson’s Disease
USP13 Inhibition Clears Lewy Bodies in a Mouse Model of Parkinson’s Disease Many age-related conditions are associated with solid aggregates in tissues that are formed of altered, damaged, or misfolded proteins. Protein aggregates are thought to be an important contributing cause of these diseases. In most cases the proteins involved in aggregate formation can and […]
Initial Evidence for the Antibiotics Azithromycin and Roxithromycin to be Senolytic
Initial Evidence for the Antibiotics Azithromycin and Roxithromycin to be Senolytic Researchers here report on two new senolytic compounds identified in the existing library of approved drugs, based on screening work in cell cultures. It is worth bearing in mind that drug candidates that demonstrate good results in cell culture quite often fail to show […]
